My approach (it may or may not apply here):

Program Mix (as the overall dry/wet FX master) – 50% as a starting point.

Preset A and Preset B Mix – 100% as starting points.

Tweak the Preset effects parameters to your liking.  You can temporarily turn Program Mix=100% to focus only on the particular effect you’re after.

Often, it’s then a simple matter of dialing down the Program Mix to 25-30-35-40%, to strike a good balance between your dry input tone and its effected counterpart.

Occasionally, you may need to adjust Preset A / B Mix control(s) down from 100% (in order to fold in more targeted dry signal).  Or adjust any misbehaving levels with the Preset In or Out Gains.

Yes, the ranges from parameter to parameter (even algorithm to algorithm) are ‘curved’ differently.  But this kind of approach lets you focus first on the FX sound itself.  Once you’re satisfied, you might consider saving two versions of the Program:  One for front-of-amp; the other for send/receive as an outboard (setting Program Mix=100% or one of the Kill Dry options).